Cell Logic for Dual Coupling of a Single Class of Receptors to G s and G i Proteins
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چکیده
منابع مشابه
Cell logic for dual coupling of a single class of receptors to G(s) and G(i) proteins.
Gprotein–coupled receptors mediate transmembrane signal transduction for a variety of hormones, neurotransmitters, chemokines, and synthetic ligands. It had been thought that a given receptor couples only to a single class of heterotrimeric G proteins to achieve signaling selectivity and specificity. As a model system of G protein– coupled receptors, b-adrenergic receptor (bAR) was believed to ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2000
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.87.8.635